CRISPR-Cas9 causes more damage in the genome than thought

At present CRISPR-Cas9  produces off-target effects See video below The CRISPR-Cas9 genome editing system causes more damage in the cellular DNA than previously believed, and this is not detected by standard tests, according to a study published in Nature Biotechnology. While it...

Gene drive used in mammals for the first time. Possible effects of the genome modification of entire species

Could we change natural design without mayors consequences?  Gene drive technology allows genome of entire species to be modified, has been used for the first time in mammals (mice). The article has not yet been published, but it can already be read on the online preprint server...

New association launched for the international regulation of genome editing

With the arrival of CRISPR, gene editing has been established as a feasible reality for a multitude of applications, not only therapeutic, but also environmental, livestock and agricultural applications, among others (see the amplitude of possible uses of this technique HERE)....

Human genome “grammar” is extremely complex. Are we prepared for the genetics revolution we are living?

Human genome sequencing revealed the order of the 3 billion letters of the ADN (A, C, G and T), but not what they mean, much less the grammar that gives them meaning. Human genome grammar  A study by the Karolinska Institute in Stockholm in the edition of international science...

Duchenne muscular dystrophy could be treated with genome editing using CRISPR/Cas9 technique

Genome editing using  CRISPR/Cas9 is a promising possibility for correcting diseases due to genetic mutations (see HERE ), such as Duchenne muscular dystrophy – lethal degeneration of cardiac and skeletal muscle caused by different genetic mutations (see more HERE), which...

Genome editing and germ line modification. Medical and ethical debate

Genetic modification of the human germline that will pass to children, and to future Gene editing consists of the modification or removal of specific DNA sequences in order, for example, to correct a disease-causing mutation. Early approaches were based on the recognition of...
Posted On 28 May 2018
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Scientists cloned human embryos and modify their genome. Medical and ethical approach

The technique has 2 ethical difficulties human embryo cloning and germline modifications Over the last few months, several articles have been published reporting genome editing experiments on human embryos (See HERE  ). Now, a team of Chinese researchers has published a new study...

CRISPR: the genome editing tool reveals the keys to embryonic development

At the beginning of 2016, the United Kingdom Human Fertilisation and Embryology Authority (HFEA) announced that it had approved a request from the Francis Crick Institute to use the new genome-editing techniques in human embryos for the first time in the country. The aim was to...

Could genome sequencing in healthy persons create “sick patients for life”?

The genome sequencing in healthy persons can be useful, provided that such information is handled with the necessary confidentiality and used with the medical and ethical caution required On 27th June, the journal Annals of Internal Medicine published a study in which researchers...

CRISPR diagnoisis tool. A new biomedical breakthrough from genome editing to disease diagnosis

CRISPR techniques are gaining traction in another realm of medical technology. CRISPR diagnosis tool It has recently been announced that the CRISPR tool, used up to now in the field of genome editing, can be used in another field, namely in diagnosis, combining it with the enzyme...