US authorizes the use of CRISPR directly in the patient’s body, until now the trials was made in cells extracted of the patient

Hopes and and concerns The first clinical trial involving the use of the gene editing tool CRISPR directly in the patient (see more ) has been approved in the United States. The trial aim to treat a congenital blindeness will include around 15 patients, adults and children, in...

Same-sex parents produced in mammals. Mouse pups obtained from “exclusively” male or female pairs

See video below Scientists have managed to produce mouse pups , i.e. bimaternal or bipaternal, in experiments that have been published in Cell Stem Cell. In the aforementioned study, fertile mice were obtained from two females, and mice from two males were born from surrogate...

Legal aspects to take into account in the case of genetically modified babies in China

INTRODUCTION The news has come to light in numerous media: Chinese researcher He Jiankui and his team at SUSTech (Southern University of Science and Technology of China) in Shenzhen have produced the first two genetically-modified human beings using the CRISPR-CAS9 technique...

CRISPR-mediated therapeutic editing corrects a genetic disease in mice’s fetuses. May it pave way in humans?

Researchers at the Children’s Hospital of Philadelphia Institute (CHOP) and the University of Pennsylvania have published the first proof-of-concept demonstrating the possibility of using CRISPR gene editing to cure diseases in utero (Nature Medicine). Using this strategy, they...

“Gene-edited babies” in China. What has said the coinventor of CRISPR technique, Jennifer Doudna?

Jennifer Doudna said, “It is a matter of when and where the gene editing technology will be used in human embryos”. As we commented HERE a Chinese scientist claimed he has used the CRISPR gene-editing science to produce two infants who will be resistant to HIV...

Cocaine effects and overdose successfully treated with CRISPR gene editing in mice

Researchers at the University of Chicago have used the CRISPR gene editing tool to treat cocaine addiction in mice, and suggest that it will be feasible to use this treatment in people. Methodology. Producing an artificial enzyme  The study, published in Nature Biomedical...

The first genetically modified babies in China

A number of media outlets have reported the news: Chinese scientists produce genetically edited babies for the first time (see HERE and HERE. According to He Jiankui, the Chinese scientist responsible, his team has managed to obtain the first babies genetically modified in the...

Cell life extended, authors suggest that this finding could increase human life expectancy

Building on two decades of research, investigators at UT Southwestern medical school have determined that “cellular housekeeping” (all cells and code for proteins that are essential for basic cell growth and metabolism)  can extend the lifespan and improve the health...

New association launched for the international regulation of genome editing

With the arrival of CRISPR, gene editing has been established as a feasible reality for a multitude of applications, not only therapeutic, but also environmental, livestock and agricultural applications, among others (see the amplitude of possible uses of this technique HERE)....

Duchenne muscular dystrophy could be treated with genome editing using CRISPR/Cas9 technique

Genome editing using  CRISPR/Cas9 is a promising possibility for correcting diseases due to genetic mutations (see HERE ), such as Duchenne muscular dystrophy – lethal degeneration of cardiac and skeletal muscle caused by different genetic mutations (see more HERE), which...