Same-sex parents produced in mammals. Mouse pups obtained from “exclusively” male or female pairs

See video below Scientists have managed to produce mouse pups , i.e. bimaternal or bipaternal, in experiments that have been published in Cell Stem Cell. In the aforementioned study, fertile mice were obtained from two females, and mice from two males were born from surrogate...

Legal aspects to take into account in the case of genetically modified babies in China

INTRODUCTION The news has come to light in numerous media: Chinese researcher He Jiankui and his team at SUSTech (Southern University of Science and Technology of China) in Shenzhen have produced the first two genetically-modified human beings using the CRISPR-CAS9 technique...

CRISPR-mediated therapeutic editing corrects a genetic disease in mice’s fetuses. May it pave way in humans?

Researchers at the Children’s Hospital of Philadelphia Institute (CHOP) and the University of Pennsylvania have published the first proof-of-concept demonstrating the possibility of using CRISPR gene editing to cure diseases in utero (Nature Medicine). Using this strategy, they...

“Gene-edited babies” in China. What has said the coinventor of CRISPR technique, Jennifer Doudna?

Jennifer Doudna said, “It is a matter of when and where the gene editing technology will be used in human embryos”. As we commented HERE a Chinese scientist claimed he has used the CRISPR gene-editing science to produce two infants who will be resistant to HIV...

Cocaine effects and overdose successfully treated with CRISPR gene editing in mice

Researchers at the University of Chicago have used the CRISPR gene editing tool to treat cocaine addiction in mice, and suggest that it will be feasible to use this treatment in people. Methodology. Producing an artificial enzyme  The study, published in Nature Biomedical...

Current knowledge does not justify universal genetic tests for newborns, scientists and ethicists affirms

As discussed in an article in The Lancet, Francis Collins, director of the United States National Institutes of Health – NIH, said in 2014 that “over the course of the next few decades, the availability of cheap, efficient DNA technology will lead to a medical...

DNA methylation is a sophisticated biological mechanism with objective implications in biology and medicine

An article in Lancet approaches the DNA  methylation (the incorporation of molecular “marks” on the DNA) who constitutes a marking system that holds instructions on how and when the genetic information contained in the DNA should be read. Unlike the genomic structure, which is...

The first genetically modified babies in China

A number of media outlets have reported the news: Chinese scientists produce genetically edited babies for the first time (see HERE and HERE. According to He Jiankui, the Chinese scientist responsible, his team has managed to obtain the first babies genetically modified in the...

Gene drive used in mammals for the first time. Possible effects of the genome modification of entire species

Could we change natural design without mayors consequences?  Gene drive technology allows genome of entire species to be modified, has been used for the first time in mammals (mice). The article has not yet been published, but it can already be read on the online preprint server...

Cell life extended, authors suggest that this finding could increase human life expectancy

Building on two decades of research, investigators at UT Southwestern medical school have determined that “cellular housekeeping” (all cells and code for proteins that are essential for basic cell growth and metabolism)  can extend the lifespan and improve the health...