The father’s age may determine genetic mutations in his children that do not pre-exist in them

It is nothing new to say that the father’s age can affect the health of his children, and especially that these children may have genetic problems. This appears to be confirmed in an article published in Nature, in which the authors evaluated the existence of “de novo” genetic...

US authorizes the use of CRISPR directly in the patient’s body, until now the trials was made in cells extracted of the patient

Hopes and and concerns The first clinical trial involving the use of the gene editing tool CRISPR directly in the patient (see more ) has been approved in the United States. The trial aim to treat a congenital blindeness will include around 15 patients, adults and children, in...

Large-scale genetic studies do not include a racially and ethnically diverse population that greatly affects global health

A large study published in Cell titled The Missing Diversity in Human Genetic Studies affirms that the majority of studies of genetic association with disease have been performed in Europeans, what has a negative effect in global health, and proposes solutions (read entire...

The scientific dogma that only mother’s mitochondria is inherited has been questioned which could could affect various major lines of investigation

This discovery has been a shock for those fields that are based on this “dogma” of biology, such as the study of human evolution or the development of nuclear transfer techniques Until very recently, it was thought that mitochondria, small cellular components...

Same-sex parents produced in mammals. Mouse pups obtained from “exclusively” male or female pairs

See video below Scientists have managed to produce mouse pups , i.e. bimaternal or bipaternal, in experiments that have been published in Cell Stem Cell. In the aforementioned study, fertile mice were obtained from two females, and mice from two males were born from surrogate...

Legal aspects to take into account in the case of genetically modified babies in China

INTRODUCTION The news has come to light in numerous media: Chinese researcher He Jiankui and his team at SUSTech (Southern University of Science and Technology of China) in Shenzhen have produced the first two genetically-modified human beings using the CRISPR-CAS9 technique...

CRISPR-mediated therapeutic editing corrects a genetic disease in mice’s fetuses. May it pave way in humans?

Researchers at the Children’s Hospital of Philadelphia Institute (CHOP) and the University of Pennsylvania have published the first proof-of-concept demonstrating the possibility of using CRISPR gene editing to cure diseases in utero (Nature Medicine). Using this strategy, they...

“Gene-edited babies” in China. What has said the coinventor of CRISPR technique, Jennifer Doudna?

Jennifer Doudna said, “It is a matter of when and where the gene editing technology will be used in human embryos”. As we commented HERE a Chinese scientist claimed he has used the CRISPR gene-editing science to produce two infants who will be resistant to HIV...

Cocaine effects and overdose successfully treated with CRISPR gene editing in mice

Researchers at the University of Chicago have used the CRISPR gene editing tool to treat cocaine addiction in mice, and suggest that it will be feasible to use this treatment in people. Methodology. Producing an artificial enzyme  The study, published in Nature Biomedical...

Current knowledge does not justify universal genetic tests for newborns, scientists and ethicists affirms

As discussed in an article in The Lancet, Francis Collins, director of the United States National Institutes of Health – NIH, said in 2014 that “over the course of the next few decades, the availability of cheap, efficient DNA technology will lead to a medical...