Therapeutic potential of Cas9-based epigenetic gene activation is proved in mice. VIDEO

 The Belmonte lab’s advanced in vivo Cas9-based epigenetic gene activation system in mice Salk scientists have created a new version technique of the CRISPR/Cas9 genome editing technology that allows them to activate genes without creating breaks in the DNA, potentially...

Advanced techniques reveal the human brain’s impressive neuronal diversification

No two neurons are alike. What does that mean for brain function? Brain cells may be as unique as the people to which they belong. This genetic, molecular, and morphological diversity of the brain leads to the functional variation that is likely necessary for the higher-order...

Is it ethical to use gene editing to extend human life?

This technique for extending human life has a risk-benefit clearly negative At present, genome editing techniques, especially CRISPR-Cas-9, seems to open up a whole range of promising applications in the fields of medicine, agriculture, animal husbandry and protection of the...

Scientists cloned human embryos and modify their genome. Medical and ethical approach

The technique has 2 ethical difficulties human embryo cloning and germline modifications Over the last few months, several articles have been published reporting genome editing experiments on human embryos (See HERE  ). Now, a team of Chinese researchers has published a new study...

Behavior of the father before conception affects the child’s development

A recent article published in the journal JAMA  states that a man’s behavior and his exposure to different environmental factors before conception may determine the development and future health of his offspring, and can result in obesity, diabetes, cardiovascular diseases,...

CRISPR: the genome editing tool reveals the keys to embryonic development

At the beginning of 2016, the United Kingdom Human Fertilisation and Embryology Authority (HFEA) announced that it had approved a request from the Francis Crick Institute to use the new genome-editing techniques in human embryos for the first time in the country. The aim was to...

Ethical concerns in prenatal genetic tests. Could they be used for discriminate before birth?

Non-invasive prenatal genetic testing NIPT is a method that uses maternal blood to detect fetal chromosomal abnormalities and other characteristics in early pregnancy, with no risks for the fetus. This makes it a promising method from both a medical and ethical perspective,...

Could genome sequencing in healthy persons create “sick patients for life”?

The genome sequencing in healthy persons can be useful, provided that such information is handled with the necessary confidentiality and used with the medical and ethical caution required On 27th June, the journal Annals of Internal Medicine published a study in which researchers...

Human genetic architecture, mapped for the first time, shows objective sexual differences

Men and women is not just a social construct as affirm gender ideology. This work provides evidences of the sex-differential transcriptome and its importance to human entire body and physiology. Around 6,500 genes with activity that was biased toward one sex or the other in at...

CRISPR diagnoisis tool. A new biomedical breakthrough from genome editing to disease diagnosis

CRISPR techniques are gaining traction in another realm of medical technology. CRISPR diagnosis tool It has recently been announced that the CRISPR tool, used up to now in the field of genome editing, can be used in another field, namely in diagnosis, combining it with the enzyme...