“Gene-edited babies” in China. What has said the coinventor of CRISPR technique, Jennifer Doudna?

Jennifer Doudna said, “It is a matter of when and where the gene editing technology will be used in human embryos”. As we commented HERE a Chinese scientist claimed he has used the CRISPR gene-editing science to produce two infants who will be resistant to HIV...

Cocaine effects and overdose successfully treated with CRISPR gene editing in mice

Researchers at the University of Chicago have used the CRISPR gene editing tool to treat cocaine addiction in mice, and suggest that it will be feasible to use this treatment in people. Methodology. Producing an artificial enzyme  The study, published in Nature Biomedical...

Current knowledge does not justify universal genetic tests for newborns, scientists and ethicists affirms

As discussed in an article in The Lancet, Francis Collins, director of the United States National Institutes of Health – NIH, said in 2014 that “over the course of the next few decades, the availability of cheap, efficient DNA technology will lead to a medical...

DNA methylation is a sophisticated biological mechanism with objective implications in biology and medicine

An article in Lancet approaches the DNA  methylation (the incorporation of molecular “marks” on the DNA) who constitutes a marking system that holds instructions on how and when the genetic information contained in the DNA should be read. Unlike the genomic structure, which is...

Bioethical approach of the first genetically modified babies in China

A number of media outlets have reported the news: Chinese scientists produce genetically edited babies for the first time (see HERE and HERE. According to He Jiankui, the Chinese scientist responsible, his team has managed to obtain the first babies genetically modified in...

Gene drive used in mammals for the first time. Possible effects of the genome modification of entire species

Could we change natural design without mayors consequences?  Gene drive technology allows genome of entire species to be modified, has been used for the first time in mammals (mice). The article has not yet been published, but it can already be read on the online preprint server...

Cell life extended, authors suggest that this finding could increase human life expectancy

Building on two decades of research, investigators at UT Southwestern medical school have determined that “cellular housekeeping” (all cells and code for proteins that are essential for basic cell growth and metabolism)  can extend the lifespan and improve the health...

New association launched for the international regulation of genome editing

With the arrival of CRISPR, gene editing has been established as a feasible reality for a multitude of applications, not only therapeutic, but also environmental, livestock and agricultural applications, among others (see the amplitude of possible uses of this technique HERE)....

Gene therapy recent clinical applications

As we said in a previous article gene therapy is facing a new promising stage (see WHY). On 9 January this year, a review was published in JAMA on the latest advances in gene therapy, making reference to specific advances in humans. The first refers to gene therapy treatment of a...

Human genome “grammar” is extremely complex. Are we prepared for the genetics revolution we are living?

Human genome sequencing revealed the order of the 3 billion letters of the ADN (A, C, G and T), but not what they mean, much less the grammar that gives them meaning. Human genome grammar  A study by the Karolinska Institute in Stockholm in the edition of international science...