Tag

In hereditary genetic diseases, the possibility of using gene therapy before birth has opened a new possibility for treating these serious diseases. Now, a study conducted in mice has just been published in Nature Medicine (read HERE), in which treatment was applied to mice with...

Hopes and and concerns The first clinical trial involving the use of the gene editing tool CRISPR directly in the patient (see more ) has been approved in the United States. The trial aim to treat a congenital blindeness will include around 15 patients, adults and children, in...

As far as we know, it is the first time that a cancer therapy achieved terminal cancer eliminating all cancer cells  Judy – who lives in Florida – had spreading, advanced breast cancer that could not be treated with conventional therapy. She had tennis ball-sized...

With the arrival of CRISPR, gene editing has been established as a feasible reality for a multitude of applications, not only therapeutic, but also environmental, livestock and agricultural applications, among others (see the amplitude of possible uses of this technique HERE)....

DNA tests for cancer treatments announced by NHS Hospitals  People in England will have access to DNA tests on an unprecedented scale from the autumn. It will be the first public health service in the world to routinely offer genomic medicine to certain patients. Hospitals across...

In order to introduce DNA into cells, gene therapy  uses viruses, but now experimental studies in animals have suggested that when high doses of viruses are used, the process is not as safe as believed. Recent experiments conducted by James Wilson at the University of...

As we said in a previous article gene therapy is facing a new promising stage (see WHY). On 9 January this year, a review was published in JAMA on the latest advances in gene therapy, making reference to specific advances in humans. The first refers to gene therapy treatment of a...

Genome editing using  CRISPR/Cas9 is a promising possibility for correcting diseases due to genetic mutations (see HERE ), such as Duchenne muscular dystrophy – lethal degeneration of cardiac and skeletal muscle caused by different genetic mutations (see more HERE), which...

Gene therapies are surely the most complex drugs in history. After a traditional trial-and-error phase, they now face a more promising chapter that is not without risks. Forty-five years ago in Science, Theodore Friedmann of the University of California, San Diego prophetically...

 The Belmonte lab’s advanced in vivo Cas9-based epigenetic gene activation system in mice Salk scientists have created a new version technique of the CRISPR/Cas9 genome editing technology that allows them to activate genes without creating breaks in the DNA, potentially...