The situation of the clinical use of stem cells

In January 2017, an article was published in JAMA (The Promise of Palliative Care – Translating Clinical Trials to Clinical Care) which, in our opinion, summarises the situation of the clinical use of stem cells extremely well. It begins by referring to the possible sources...

Serotonin produced from neurons obtained with iPS and embryonic stem cells

Serotonin is implicated in functions as important as humour, sadness, feelings of aggression, anxiety and sleep disturbances, among others. A deficiency in serotonin release has been related with schizophrenia, depression, bipolar disorder, obsessive-compulsive disorders, chronic...

Patient’s own menstrual blood stem cells used to treat Asherman’s syndrome

Infertility treatment.”The best option for endometrial regeneration in patients with Asherman’s syndrome.” Asherman’s syndrome is an acquired uterine abnormality characterised by the presence of intrauterine adhesions, and which clinically causes...

First cell gene therapy to treat “Bubble boy” disease has been legalised in Europe

Last July, an article was published in medical journal Blood, which described the success of a cell gene therapy modality to treat the immunodeficiency caused by adenosine deaminase deficiency – “Bubble boy” disease. This is a disease that alters purine...

New breakthrough in the treatment of Crohn’s disease using cell therapy

Crohn’s disease treatment using cell therapy. In 2009, Spanish researchers (see HERE) proposed the use of mesenchymal stem cells for the treatment of fistulas in Crohn’s disease. The findings of the first phase 3 randomised, double-blind, placebo-controlled clinical...

Functional artificial eggs obtained for the first time from mouse skin

Scientists in Japan have transformed mouse skin cells into eggs and have managed to obtain fertile offspring after their fertilisation (See Nature article HERE). This study represents the first production of eggs completely in vitro. In 2012, mouse skin cells were reprogrammed...

Cell therapy clinics questioned. Technical and ethical aptitude of clincs in North America

Today in the United States there are 350 cell therapy centres offering stem cell-based treatments for autism, cystic fibrosis, multiple sclerosis and other diseases. Cell therapy clinics questioned because the vast majority lack not only approval by the United States medicines...

Stem cells and the production of organoids at the forefront of biomedical science

There are topics in which biomedical interest merges with ethical interest. One of these is undoubtedly the subject of stem cells wich appears to be the biomedical science forefront. Few issues in the biomedical sciences arouse as much interest as these, and for this reason, the...

Fraudulent cell therapy. South Korea, trying to restore its tarnished image in the field, increases safety regulations

South Korea has been trying to restore its tarnished image in the field after the fall of one of its stellar stem-cell scientists, Woo Suk Hwang, who was convicted in 2009 for embezzlement and bioethics violations after falsifying results. The country has begun to regain...

What is the current clinical usefulness of stem cell treatments, embryonic and iPS cells?

Human adult stem cells (iPS) have been found to be the most clinically useful human cells for therapeutic purposes Pluripotent cells (iPS) are defined as those from which cells of different tissue types can be obtained. These can be obtained either from preimplantation human...