Pluripotent stem cells used for regenrative medicine risks. They can develop mutations that favor the production of cancer cells

It should be crucial to check pluripotent cell lines (embryonic and iPS cells) before clinical testing before their use in regenerative medicine The production of pluripotent stem cells, from which virtually all types of cells can be obtained, may be of great use for the...

iPS cells are also used to gain in depth knowledge of diseases. Now Parkinson disease is being more studied in depth by this technique

It appears to have been confirmed that the α-Synuclein gene is the one primarily linked to Parkinson’s disease, while the G209 (p.A53T) mutation of this gene causes a type of Parkinson’s disease characterized by early and severe onset of symptoms. It has now been...

Umbilical cord blood banks in Spain. Units stored are 10% of the total number worldwide

Increase in applications of cord blood cells in treatment of various diseases (see HERE) encourage parents The key factors encouraging expectant parents to preserve cord blood include the vast rise in the rate of hematopoietic stem cell transplantation, the vast advancements in...
Posted On 25 Sep 2017
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Ten years since the discovery of iPS cells. The current state of their clinical application

  Rev Clin Esp. 2017 Jan – Feb;217(1):30-34. doi: 10.1016/j.rce.2016.08.003. Epub 2016 Oct 5. Justo Aznar Ph.D. MD Julio Tudela Pharm Ph.D. Institute of Life Science – Bioethics Observatory Catholic University of Valencia – Spain iPS cells current clinical...

Stem cell research. The two sides of the coin

Science facing market The “heads” of stem cell research Stem cells today represent a great hope for the future of regenerative medicine due to their ability to differentiate into cell lines of almost any tissue, making them a promising therapeutic option for many...

The situation of the clinical use of stem cells

In January 2017, an article was published in JAMA (The Promise of Palliative Care – Translating Clinical Trials to Clinical Care) which, in our opinion, summarises the situation of the clinical use of stem cells extremely well. It begins by referring to the possible sources...

Patient’s own menstrual blood stem cells used to treat Asherman’s syndrome

Infertility treatment.”The best option for endometrial regeneration in patients with Asherman’s syndrome.” Asherman’s syndrome is an acquired uterine abnormality characterised by the presence of intrauterine adhesions, and which clinically causes...

New breakthrough in the treatment of Crohn’s disease using cell therapy

Crohn’s disease treatment using cell therapy. In 2009, Spanish researchers (see HERE) proposed the use of mesenchymal stem cells for the treatment of fistulas in Crohn’s disease. The findings of the first phase 3 randomised, double-blind, placebo-controlled clinical...

Functional artificial eggs obtained for the first time from mouse skin

Scientists in Japan have transformed mouse skin cells into eggs and have managed to obtain fertile offspring after their fertilisation (See Nature article HERE). This study represents the first production of eggs completely in vitro. In 2012, mouse skin cells were reprogrammed...

Cell therapy clinics questioned. Technical and ethical aptitude of clincs in North America

Today in the United States there are 350 cell therapy centres offering stem cell-based treatments for autism, cystic fibrosis, multiple sclerosis and other diseases. Cell therapy clinics questioned because the vast majority lack not only approval by the United States medicines...
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