Cardiac muscle cells, that drive the beating of the heart, developed from iPS cells

Cardiomyocytes produced with success One of the possibilities for the clinical-experimental use of iPS cells is to develop human-like tissues -organoids- for use in basic research or in preclinical therapeutic studies. Now, using iPS cells obtained from primates, a team from...

A step to a cancer vaccine. A promising animal trial with autologous iPS cells

 Cancer vaccine advances A new possible use of iPS cells (see medical and ethical advantages of iPS cells treatment) has been opened up, using them as a type of vaccine against cancer. According to a recent study published in journal CELL (see HERE), autologous iPS cells (i.e....

Cancer cell therapy, still experimental, beats terminal breast cancer woman with secondary cancers

As far as we know, it is the first time that a cancer therapy achieved terminal cancer eliminating all cancer cells  Judy – who lives in Florida – had spreading, advanced breast cancer that could not be treated with conventional therapy. She had tennis ball-sized...

For now, iPS cells have revolutionized the laboratory bench more than bedside

In a recent article, Amélie Rezza discussed the current use of iPS cells, understanding as such adult cells reprogrammed following a technique discovered by Yamanaka. See HERE our site for furthermore information. After the development of these cells, it was thought that they...

Understanding the biological mechanisms of aging. Aging retardation is achieved in mice

A biological topic of great interest is to understand the mechanisms of aging. The nervous system is known to clearly affect aging, especially the hypothalamus, but the mechanism by which it occurs is presently unknown. Cells that had been genetically engineered to survive in the...

Pluripotent stem cells used for regenrative medicine risks. They can develop mutations that favor the production of cancer cells

It should be crucial to check pluripotent cell lines (embryonic and iPS cells) before clinical testing before their use in regenerative medicine The production of pluripotent stem cells, from which virtually all types of cells can be obtained, may be of great use for the...

The future of iPS – induced pluripotent stem cells. New finding increases tremendously their potential for clinical use

Cells now can be obtained from anonymous donors, however, and stored in a cell bank, the costs would be reduced significantly, and their potential for clinical use would increase tremendously A recent article published in Nature discussed some specific aspects regarding the...

iPS cells are also used to gain in depth knowledge of diseases. Now Parkinson disease is being more studied in depth by this technique

It appears to have been confirmed that the α-Synuclein gene is the one primarily linked to Parkinson’s disease, while the G209 (p.A53T) mutation of this gene causes a type of Parkinson’s disease characterized by early and severe onset of symptoms. It has now been...

Umbilical cord blood banks in Spain. Units stored are 10% of the total number worldwide

Increase in applications of cord blood cells in treatment of various diseases (see HERE) encourage parents The key factors encouraging expectant parents to preserve cord blood include the vast rise in the rate of hematopoietic stem cell transplantation, the vast advancements in...
Posted On 25 Sep 2017
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Pulmonary organoids produced from human iPS cells in three dimensions (3D)

Lung organoids have been produced from human pluripotent stem (iPS) cells that contain various components of lung tissue, and even airways and alveolar structures (see HERE). Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D)...