Understanding the biological mechanisms of aging. Aging retardation is achieved in mice

A biological topic of great interest is to understand the mechanisms of aging. The nervous system is known to clearly affect aging, especially the hypothalamus, but the mechanism by which it occurs is presently unknown. Cells that had been genetically engineered to survive in the...

Pluripotent stem cells used for regenrative medicine risks. They can develop mutations that favor the production of cancer cells

It should be crucial to check pluripotent cell lines (embryonic and iPS cells) before clinical testing before their use in regenerative medicine The production of pluripotent stem cells, from which virtually all types of cells can be obtained, may be of great use for the...

The future of iPS – induced pluripotent stem cells. New finding increases tremendously their potential for clinical use

Cells now can be obtained from anonymous donors, however, and stored in a cell bank, the costs would be reduced significantly, and their potential for clinical use would increase tremendously A recent article published in Nature discussed some specific aspects regarding the...

iPS cells are also used to gain in depth knowledge of diseases. Now Parkinson disease is being more studied in depth by this technique

It appears to have been confirmed that the α-Synuclein gene is the one primarily linked to Parkinson’s disease, while the G209 (p.A53T) mutation of this gene causes a type of Parkinson’s disease characterized by early and severe onset of symptoms. It has now been...

Umbilical cord blood banks in Spain. Units stored are 10% of the total number worldwide

Increase in applications of cord blood cells in treatment of various diseases (see HERE) encourage parents The key factors encouraging expectant parents to preserve cord blood include the vast rise in the rate of hematopoietic stem cell transplantation, the vast advancements in...
Posted On 25 Sep 2017
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Pulmonary organoids produced from human iPS cells in three dimensions (3D)

Lung organoids have been produced from human pluripotent stem (iPS) cells that contain various components of lung tissue, and even airways and alveolar structures (see HERE). Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D)...

Review of the last advances in the producing of a functional intestine

A new step has been done to grow something therapeutically useful intestine in the long run (see the last article we published HERE). When it comes to growing intestines, the first inch is the hardest -, especially in a Petri dish. Scientists at Cincinnati Children’s...

Ten years since the discovery of iPS cells. The current state of their clinical application

  Rev Clin Esp. 2017 Jan – Feb;217(1):30-34. doi: 10.1016/j.rce.2016.08.003. Epub 2016 Oct 5. Justo Aznar Ph.D. MD Julio Tudela Pharm Ph.D. Institute of Life Science – Bioethics Observatory Catholic University of Valencia – Spain iPS cells current clinical...

Stem cell research. The two sides of the coin

Science facing market The “heads” of stem cell research Stem cells today represent a great hope for the future of regenerative medicine due to their ability to differentiate into cell lines of almost any tissue, making them a promising therapeutic option for many...

Intestinal tissue produced from embryonic stem cells and iPS cells

The intestinal nervous system controls several functions of the gastrointestinal tract, and when impaired causes bowel abnormalities. Now, a group of American researchers has generated intestinal tissue from embryonic and iPS cells (this last hasn’t ethics problems), using...