Human-mouse hybrids created with sperm produced from human testicular stem cells

According to a recent article (see HERE), a team of researchers has managed to produce human functional spermatids (as sperm precursor cells are known) from human spermatogonial stem cells (SSC), testicular sperm cell precursors.  The SSCs were isolated and identified...

Artificial organoids generated from cancer cells

Organoids mimic therapies responses We have published several articles about Potential applications of organoids that mimic different organs. We concluded that this creation of organic structures (organoids) similar to others in our body may have objective biomedical...

Cancer cell therapy, still experimental, beats terminal breast cancer woman with secondary cancers

As far as we know, it is the first time that a cancer therapy achieved terminal cancer eliminating all cancer cells  Judy – who lives in Florida – had spreading, advanced breast cancer that could not be treated with conventional therapy. She had tennis ball-sized...

For now, iPS cells have revolutionized the laboratory bench more than bedside

In a recent article, Amélie Rezza discussed the current use of iPS cells, understanding as such adult cells reprogrammed following a technique discovered by Yamanaka. See HERE our site for furthermore information. After the development of these cells, it was thought that they...

Ethical debate. “Right to try laws” allow terminally ill patients access experimental treatments

The U.S Senate on easily passed legislation that aims to help terminally ill patients access experimental treatments (for example, stem cells therapies) under so-called “right to try” laws.  Now the full House will vote on it (STATS, January 8, 2017). The bill would establish...

Understanding the biological mechanisms of aging. Aging retardation is achieved in mice

A biological topic of great interest is to understand the mechanisms of aging. The nervous system is known to clearly affect aging, especially the hypothalamus, but the mechanism by which it occurs is presently unknown. Cells that had been genetically engineered to survive in the...

The future of iPS – induced pluripotent stem cells. New finding increases tremendously their potential for clinical use

Cells now can be obtained from anonymous donors, however, and stored in a cell bank, the costs would be reduced significantly, and their potential for clinical use would increase tremendously A recent article published in Nature discussed some specific aspects regarding the...

Cells from human umbilical cord blood revitalized part of aged rats’ brain

Cord blood stem cells revitalized part of the brain in aged rats. Umbilical cord blood is known to contain stem cells that can be used for different clinical objectives  (see HERE), especially in the promotion of cell banks. Now, a new possibility for the use of umbilical cord...

Pulmonary organoids produced from human iPS cells in three dimensions (3D)

Lung organoids have been produced from human pluripotent stem (iPS) cells that contain various components of lung tissue, and even airways and alveolar structures (see HERE). Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D)...

Legal status of human-animal chimeras – hybrid embryos

In addition to the biomedical and bioethical problems raised by human-animal hybridization, there are also objective legal problems. A recent article in the Journal of Medical Ethics (2014; 40, 284-285) reviewed this topic following a debate in the United Kingdom (UK) House of...