Cell life extended, authors suggest that this finding could increase human life expectancy

Building on two decades of research, investigators at UT Southwestern medical school have determined that “cellular housekeeping” (all cells and code for proteins that are essential for basic cell growth and metabolism)  can extend the lifespan and improve the health...

Cardiac muscle cells, that drive the beating of the heart, developed from iPS cells

Cardiomyocytes produced with success One of the possibilities for the clinical-experimental use of iPS cells is to develop human-like tissues -organoids- for use in basic research or in preclinical therapeutic studies. Now, using iPS cells obtained from primates, a team from...

Cryopreserve ovarian tissue from prepubertal girls who are to undergo cancer treatment. Medical and ethical approach

When a cancer patient is treated with radio and/or chemotherapy, they can become infertile, both men and women. Consequently, ovarian tissue cryopreservation prior to treatment is recommended in women, with the cryopreserved tissue then transferred again to the patient if she...

Ears made in China, using 3D printing technique, are implanted in 5 children

A team of Chinese scientists has been able to implant ears created using an experimental technology that combines cultured patient’s cells with 3D printing in five children. The children suffered from microtia, a congenital external ear deformity that affects one in every...

Transplant of cryopreserved ovarian tissue to leukemia surivivor women. A healthy child have already been born

First child healthy born from a leukemia cancer survivor More than 80 children have already been born worldwide after cryopreserved ovarian tissue-transplantation in women who, due to disease or medical treatment, could lose the chance to have children in the future. Over the...

For now, iPS cells have revolutionized the laboratory bench more than bedside

In a recent article, Amélie Rezza discussed the current use of iPS cells, understanding as such adult cells reprogrammed following a technique discovered by Yamanaka. See HERE our site for furthermore information. After the development of these cells, it was thought that they...

Therapeutic potential of Cas9-based epigenetic gene activation is proved in mice. VIDEO

 The Belmonte lab’s advanced in vivo Cas9-based epigenetic gene activation system in mice Salk scientists have created a new version technique of the CRISPR/Cas9 genome editing technology that allows them to activate genes without creating breaks in the DNA, potentially...

Understanding the biological mechanisms of aging. Aging retardation is achieved in mice

A biological topic of great interest is to understand the mechanisms of aging. The nervous system is known to clearly affect aging, especially the hypothalamus, but the mechanism by which it occurs is presently unknown. Cells that had been genetically engineered to survive in the...

Pluripotent stem cells used for regenrative medicine risks. They can develop mutations that favor the production of cancer cells

It should be crucial to check pluripotent cell lines (embryonic and iPS cells) before clinical testing before their use in regenerative medicine The production of pluripotent stem cells, from which virtually all types of cells can be obtained, may be of great use for the...

The future of iPS – induced pluripotent stem cells. New finding increases tremendously their potential for clinical use

Cells now can be obtained from anonymous donors, however, and stored in a cell bank, the costs would be reduced significantly, and their potential for clinical use would increase tremendously A recent article published in Nature discussed some specific aspects regarding the...