Cryopreserve ovarian tissue from prepubertal girls who are to undergo cancer treatment. Medical and ethical approach

When a cancer patient is treated with radio and/or chemotherapy, they can become infertile, both men and women. Consequently, ovarian tissue cryopreservation prior to treatment is recommended in women, with the cryopreserved tissue then transferred again to the patient if she...

Ears made in China, using 3D printing technique, are implanted in 5 children

A team of Chinese scientists has been able to implant ears created using an experimental technology that combines cultured patient’s cells with 3D printing in five children. The children suffered from microtia, a congenital external ear deformity that affects one in every...

Transplant of cryopreserved ovarian tissue to leukemia surivivor women. A healthy child have already been born

First child healthy born from a leukemia cancer survivor More than 80 children have already been born worldwide after cryopreserved ovarian tissue-transplantation in women who, due to disease or medical treatment, could lose the chance to have children in the future. Over the...

For now, iPS cells have revolutionized the laboratory bench more than bedside

In a recent article, Amélie Rezza discussed the current use of iPS cells, understanding as such adult cells reprogrammed following a technique discovered by Yamanaka. See HERE our site for furthermore information. After the development of these cells, it was thought that they...

Therapeutic potential of Cas9-based epigenetic gene activation is proved in mice. VIDEO

 The Belmonte lab’s advanced in vivo Cas9-based epigenetic gene activation system in mice Salk scientists have created a new version technique of the CRISPR/Cas9 genome editing technology that allows them to activate genes without creating breaks in the DNA, potentially...

Understanding the biological mechanisms of aging. Aging retardation is achieved in mice

A biological topic of great interest is to understand the mechanisms of aging. The nervous system is known to clearly affect aging, especially the hypothalamus, but the mechanism by which it occurs is presently unknown. Cells that had been genetically engineered to survive in the...

Pluripotent stem cells used for regenrative medicine risks. They can develop mutations that favor the production of cancer cells

It should be crucial to check pluripotent cell lines (embryonic and iPS cells) before clinical testing before their use in regenerative medicine The production of pluripotent stem cells, from which virtually all types of cells can be obtained, may be of great use for the...

The future of iPS – induced pluripotent stem cells. New finding increases tremendously their potential for clinical use

Cells now can be obtained from anonymous donors, however, and stored in a cell bank, the costs would be reduced significantly, and their potential for clinical use would increase tremendously A recent article published in Nature discussed some specific aspects regarding the...

Cells from human umbilical cord blood revitalized part of aged rats’ brain

Cord blood stem cells revitalized part of the brain in aged rats. Umbilical cord blood is known to contain stem cells that can be used for different clinical objectives  (see HERE), especially in the promotion of cell banks. Now, a new possibility for the use of umbilical cord...

Pulmonary organoids produced from human iPS cells in three dimensions (3D)

Lung organoids have been produced from human pluripotent stem (iPS) cells that contain various components of lung tissue, and even airways and alveolar structures (see HERE). Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D)...