CRISPR used in viable human embryos and germline genetic modification. An ethical approach

From an ethical point of view, the use and destruction of human embryos, members of our species and worthy of full dignity is completely unacceptable and, it should be noted,  these experiments involve genetic modification of the germline, the safety of which is still far from...

The embryo germline modification, particualrly in humans. It is an unsafe procedure

 “Absolute prohibition of such experiments” A group of clinical researchers has proposed modifying embryos using “therapies that may affect the embryo germline“. These techniques could produce changes that could be transmitted to successive generations....

Role of genetic engineering in European agriculture

Criticises the attitude of politicians, on not recognising the value of new farming technologies The scientific advisor HFFA Research GmbH has published a study entitled “ The economic, social and environmental value of plant breeding in the European Union” on the...

Ethical questions about mitochondrial replacement in humans. Three-parent baby technique

We thus consider it necessary to establish a moratorium on their use in humans, at least until more is known about these aspects. If this knowledge is obtained, ethical questions would still remain to be resolved, among which we consider the most relevant to be those related to...

Open ethical debate: Are gene editing techniques ethical in reproductive medicine?

Author’s opinion: The use of these techniques is currently medically and ethically unjustifiable. The United Kingdom has recently approved mitochondrial transfer (3 parents children) to prevent the development of mitochondrial diseases in the children of mothers affected by...

Genetic engineering of human embryos to treat diseases. An unprejudiced reflection

In the last five years, many laboratories worldwide have employed the genetic engineering technique known as CRISPR/Cas9, in the hope that it might one day be used to treat human diseases. Things seem to have accelerated in the last few days though, after the authorisation in the...

Gene editing today. All we have to know about it and our bioethical assessment

Few scientific breakthroughs have been as important as the discovery of the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats) technique as a gene editing tool. CRISPR/Cas9 is a natural system that provides bacteria with an adaptive response against viruses...

CRISPR used for the first time in humans

A team led by oncologist Lu Youou at Sichuan University in China has become the first to use the revolutionary CRISPR technique on a patient with aggressive lung cancer as part of a clinical trial at the West China Hospital, according to an article published in Nature. The use of...

Human genome. Its “grammar” is more complex than thought

Human genome sequencing revealed the order of the 3 billion letters of A, C, G and T, but not what they mean, much less the grammar that gives them meaning. A study by the Karolinska Institute in Stockholm in the latest edition of international science journal Nature (527;...

Rules for regulating genome editing – particularly gene drive

The dynamic field of research into gene editing provides an opportunity to rewrite the rules of science, says Kevin Esvelt. The emergence of gene-drive systems — which spread engineered mutations quickly through populations — means that a single released organism could eventually...