CRISPR-Cas9 causes more damage in the genome than thought

At present CRISPR-Cas9  produces off-target effects See video below The CRISPR-Cas9 genome editing system causes more damage in the cellular DNA than previously believed, and this is not detected by standard tests, according to a study published in Nature Biotechnology. While it...

Gene drive used in mammals for the first time. Possible effects of the genome modification of entire species

Could we change natural design without mayors consequences?  Gene drive technology allows genome of entire species to be modified, has been used for the first time in mammals (mice). The article has not yet been published, but it can already be read on the online preprint server...

Cancer cell therapy, still experimental, beats terminal breast cancer woman with secondary cancers

As far as we know, it is the first time that a cancer therapy achieved terminal cancer eliminating all cancer cells  Judy – who lives in Florida – had spreading, advanced breast cancer that could not be treated with conventional therapy. She had tennis ball-sized...

Cell life extended, authors suggest that this finding could increase human life expectancy

Building on two decades of research, investigators at UT Southwestern medical school have determined that “cellular housekeeping” (all cells and code for proteins that are essential for basic cell growth and metabolism)  can extend the lifespan and improve the health...

New association launched for the international regulation of genome editing

With the arrival of CRISPR, gene editing has been established as a feasible reality for a multitude of applications, not only therapeutic, but also environmental, livestock and agricultural applications, among others (see the amplitude of possible uses of this technique HERE)....

NHS will offer routinely DNA tests for cancer patients from October. How will help to treat cancer patients? Video

DNA tests for cancer treatments announced by NHS Hospitals  People in England will have access to DNA tests on an unprecedented scale from the autumn. It will be the first public health service in the world to routinely offer genomic medicine to certain patients. Hospitals across...

Monitoring must continues on gene therapy, possible risks

In order to introduce DNA into cells, gene therapy  uses viruses, but now experimental studies in animals have suggested that when high doses of viruses are used, the process is not as safe as believed. Recent experiments conducted by James Wilson at the University of...

First treatment using gene therapy, to children and adults, approved in the United States

The first treatment using gene therapy is for a serious genetic disease -Inherited Retinal Dystrophy (RD) -that causes vision loss and even blindness. The drug used is called Voretigene neparvovec-rzyl, commercial name LUXTURNA, and is indicated for patients who present with...

The Conception of Synthetic Entities from a Bioethics Perspective

Our Observatory published a paper in the journal Science and Engineering Ethics that for its relevance we want to make known our readers See HERE Synthetic biology bioethics perspective In this study, the authors affirmed that Synthetic biology opens up the possibility of...

Human-sheep hybrids created for the first time to develop organs

Human-sheep hybrids have been created for the first time by scientists at Stanford University (see New advances and challenges in the production of human-animal chimeras). The scientists grew the embryos in a surrogate sheep, allowing them to gestate up to 3 weeks (see HERE )....