Cocaine effects and overdose successfully treated with CRISPR gene editing in mice

Researchers at the University of Chicago have used the CRISPR gene editing tool to treat cocaine addiction in mice, and suggest that it will be feasible to use this treatment in people. Methodology. Producing an artificial enzyme  The study, published in Nature Biomedical...

World’s first genetically modified babies may have been born in China

A number of media outlets have reported the news: Chinese scientists produce genetically edited babies for the first time (see HERE and HERE. According to He Jiankui, the Chinese scientist responsible, his team has managed to obtain the first babies genetically modified in the...

CRISPR-Cas9 causes more damage in the genome than thought

At present CRISPR-Cas9  produces off-target effects See video below The CRISPR-Cas9 genome editing system causes more damage in the cellular DNA than previously believed, and this is not detected by standard tests, according to a study published in Nature Biotechnology. While it...

New association launched for the international regulation of genome editing

With the arrival of CRISPR, gene editing has been established as a feasible reality for a multitude of applications, not only therapeutic, but also environmental, livestock and agricultural applications, among others (see the amplitude of possible uses of this technique HERE)....

NHS will offer routinely DNA tests for cancer patients from October. How will help to treat cancer patients? Video

DNA tests for cancer treatments announced by NHS Hospitals  People in England will have access to DNA tests on an unprecedented scale from the autumn. It will be the first public health service in the world to routinely offer genomic medicine to certain patients. Hospitals across...

Monitoring must continues on gene therapy, possible risks

In order to introduce DNA into cells, gene therapy  uses viruses, but now experimental studies in animals have suggested that when high doses of viruses are used, the process is not as safe as believed. Recent experiments conducted by James Wilson at the University of...

First treatment using gene therapy, to children and adults, approved in the United States

The first treatment using gene therapy is for a serious genetic disease -Inherited Retinal Dystrophy (RD) -that causes vision loss and even blindness. The drug used is called Voretigene neparvovec-rzyl, commercial name LUXTURNA, and is indicated for patients who present with...

Gene therapy recent clinical applications

As we said in a previous article gene therapy is facing a new promising stage (see WHY). On 9 January this year, a review was published in JAMA on the latest advances in gene therapy, making reference to specific advances in humans. The first refers to gene therapy treatment of a...

CRISPR-Cas9, the gene editing tool, might cause cancer. Why does Crispr present difficulties in humans?

Editing cells’ genomes with CRISPR-Cas9  might increase the risk that the altered cells, intended to treat disease, will trigger cancer, two studies published on Monday warn [2018, Jun 11]— a potential game-changer for the companies developing CRISPR-based therapies. (Begley,...

Duchenne muscular dystrophy could be treated with genome editing using CRISPR/Cas9 technique

Genome editing using  CRISPR/Cas9 is a promising possibility for correcting diseases due to genetic mutations (see HERE ), such as Duchenne muscular dystrophy – lethal degeneration of cardiac and skeletal muscle caused by different genetic mutations (see more HERE), which...