Fetal gene therapy technique to prevent neurological damages in mice has opened a new possibility for treating humans

In hereditary genetic diseases, the possibility of using gene therapy before birth has opened a new possibility for treating these serious diseases. Now, a study conducted in mice has just been published in Nature Medicine (read HERE), in which treatment was applied to mice with...

US authorizes the use of CRISPR directly in the patient’s body, until now the trials was made in cells extracted of the patient

Hopes and and concerns The first clinical trial involving the use of the gene editing tool CRISPR directly in the patient (see more ) has been approved in the United States. The trial aim to treat a congenital blindeness will include around 15 patients, adults and children, in...

Single-cell sequencing tool opens up promising possibilities in life cycle and biomedical research

In life cycle the biologic synchronous web that shape it is still a mystery, now a new avenue of research is open Every plant, animal and fungus is made up of an intricate amalgam of cells. Each cell type has its own unique function, life cycle, and reaction to its environment....

Duchenne muscular dystrophy. Gene therapy achieves restoring the production of dystrophin in affected mouse

Duchenne muscular dystrophy (DMD)  is a hereditary potentially fatal disease as it severely affects the muscles. It occurs in 1 in every 5000 newborn males and is due to a genetic defect in the production of dystrophin, a protein found in skeletal and cardiac muscle. See our post...

Cocaine effects and overdose successfully treated with CRISPR gene editing in mice

Researchers at the University of Chicago have used the CRISPR gene editing tool to treat cocaine addiction in mice, and suggest that it will be feasible to use this treatment in people. Methodology. Producing an artificial enzyme  The study, published in Nature Biomedical...

The first genetically modified babies in China

A number of media outlets have reported the news: Chinese scientists produce genetically edited babies for the first time (see HERE and HERE. According to He Jiankui, the Chinese scientist responsible, his team has managed to obtain the first babies genetically modified in the...

CRISPR-Cas9 causes more damage in the genome than thought

At present CRISPR-Cas9  produces off-target effects See video below The CRISPR-Cas9 genome editing system causes more damage in the cellular DNA than previously believed, and this is not detected by standard tests, according to a study published in Nature Biotechnology. While it...

New association launched for the international regulation of genome editing

With the arrival of CRISPR, gene editing has been established as a feasible reality for a multitude of applications, not only therapeutic, but also environmental, livestock and agricultural applications, among others (see the amplitude of possible uses of this technique HERE)....

NHS will offer routinely DNA tests for cancer patients from October. How will help to treat cancer patients? Video

DNA tests for cancer treatments announced by NHS Hospitals  People in England will have access to DNA tests on an unprecedented scale from the autumn. It will be the first public health service in the world to routinely offer genomic medicine to certain patients. Hospitals across...

Monitoring must continues on gene therapy, possible risks

In order to introduce DNA into cells, gene therapy  uses viruses, but now experimental studies in animals have suggested that when high doses of viruses are used, the process is not as safe as believed. Recent experiments conducted by James Wilson at the University of...