Serotonin produced from neurons obtained with iPS and embryonic stem cells

Serotonin is implicated in functions as important as humour, sadness, feelings of aggression, anxiety and sleep disturbances, among others. A deficiency in serotonin release has been related with schizophrenia, depression, bipolar disorder, obsessive-compulsive disorders, chronic...

Patient’s own menstrual blood stem cells used to treat Asherman’s syndrome

Infertility treatment.”The best option for endometrial regeneration in patients with Asherman’s syndrome.” Asherman’s syndrome is an acquired uterine abnormality characterised by the presence of intrauterine adhesions, and which clinically causes...

First cell gene therapy to treat “Bubble boy” disease has been legalised in Europe

Last July, an article was published in medical journal Blood, which described the success of a cell gene therapy modality to treat the immunodeficiency caused by adenosine deaminase deficiency – “Bubble boy” disease. This is a disease that alters purine...

Retinal tissue produced from iPS cells in animals

One of the possible applications of iPS cells is in the treatment of retinal diseases. Now, a group of researchers from the Riken Institute in Kobe (Japan) see HERE has presented some interesting experiments in which they were able to produce retinal tissue from iPS cells (iPS...

Cerebral organoids produced from embryonic stem cells

A group of researchers in La Jolla, California, have produced three-dimensional  cerebral organoids (“mini-brains”) from human embryonic stem cells, later comparing the functionality of the tissue produced with samples of brain tissue from human foetuses with the same...

Public funds authorised for production of human-animal chimeras

In September 2005, the dedication of public financial aid by the National Health Institutes for experiments on transferring human stem cells to animal embryos to produce chimeras was banned. However, on 4 August this year, this ban was lifted for certain experiments, and it was...

Potential application of organoids that mimic different organs

In 2011, almost incidentally, Madeline Lancaster of the Institute of Molecular Biotechnology in Vienna managed to produce primitive retina cells and different nerve cells from embryonic stem cells. However, Lancaster and her colleagues were not the first to produce a brain...

Stem cells and the production of organoids at the forefront of biomedical science

There are topics in which biomedical interest merges with ethical interest. One of these is undoubtedly the subject of stem cells wich appears to be the biomedical science forefront. Few issues in the biomedical sciences arouse as much interest as these, and for this reason, the...

Brain tissue repair advances. Human nerve cells derived from astrocytes

Within the possibility of deriving cells from others already existing in our body, in the area of cell therapy, scientists have managed to reprogram brain astrocytes into neurons in the way to achieve brain tissue reapair. As we know, neuronal loss is thought to be definitive in...

Adult stem cells could effectively substitute embryonic cells in regenerative medicine

Many technics showed that adult stem cells could effectively substitute embryonic cells in cellular therapy. One medical and ethical problem to resolve is to find adequate substitute for the use of embryonic stem cells in regenerative and reparatory medicine. The best possibility...