Understanding the biological mechanisms of aging. Aging retardation is achieved in mice

A biological topic of great interest is to understand the mechanisms of aging. The nervous system is known to clearly affect aging, especially the hypothalamus, but the mechanism by which it occurs is presently unknown. Cells that had been genetically engineered to survive in the...

Pluripotent stem cells used for regenrative medicine risks. They can develop mutations that favor the production of cancer cells

It should be crucial to check pluripotent cell lines (embryonic and iPS cells) before clinical testing before their use in regenerative medicine The production of pluripotent stem cells, from which virtually all types of cells can be obtained, may be of great use for the...

iPS cells are also used to gain in depth knowledge of diseases. Now Parkinson disease is being more studied in depth by this technique

It appears to have been confirmed that the α-Synuclein gene is the one primarily linked to Parkinson’s disease, while the G209 (p.A53T) mutation of this gene causes a type of Parkinson’s disease characterized by early and severe onset of symptoms. It has now been...

First major step in the treatment of blood diseases from adult cells

Researchers at Weill Cornell Medicine  have developed an innovative method for obtaining blood cells (adult cells) from the endothelial cells of blood vessels (see HERE) to imporove blood diseases treatment. A peculiar characteristic of this technique is that abundant blood cells...

Cells from human umbilical cord blood revitalized part of aged rats’ brain

Cord blood stem cells revitalized part of the brain in aged rats. Umbilical cord blood is known to contain stem cells that can be used for different clinical objectives  (see HERE), especially in the promotion of cell banks. Now, a new possibility for the use of umbilical cord...

New clinical celular trial for treatment of Parkinson’s disease injecting stemcells in the patient brain

A first step to a Parkinson treatment with stem cells. The first clinical trial conducted in China (see HERE) to treat Parkinson’s disease and age-related macular degeneration and the second most common neurodegenerative disorder is to be launched shortly. In the next few...

Review of the last advances in the producing of a functional intestine

A new step has been done to grow something therapeutically useful intestine in the long run (see the last article we published HERE). When it comes to growing intestines, the first inch is the hardest -, especially in a Petri dish. Scientists at Cincinnati Children’s...

Ten years since the discovery of iPS cells. The current state of their clinical application

  Rev Clin Esp. 2017 Jan – Feb;217(1):30-34. doi: 10.1016/j.rce.2016.08.003. Epub 2016 Oct 5. Justo Aznar Ph.D. MD Julio Tudela Pharm Ph.D. Institute of Life Science – Bioethics Observatory Catholic University of Valencia – Spain iPS cells current clinical...

Stem cell research. The two sides of the coin

Science facing market The “heads” of stem cell research Stem cells today represent a great hope for the future of regenerative medicine due to their ability to differentiate into cell lines of almost any tissue, making them a promising therapeutic option for many...

The situation of the clinical use of stem cells

In January 2017, an article was published in JAMA (The Promise of Palliative Care – Translating Clinical Trials to Clinical Care) which, in our opinion, summarises the situation of the clinical use of stem cells extremely well. It begins by referring to the possible sources...