International discussion has been proposed about ethical use of embryoids, human embryo-like organoids in experiments

An article published in Nature, signed by notable personalities in the area of bioethics, discusses the ethical implications of embryoids (organoids) or embryo models, in vitro cell aggregates that model various regions of the embryo to allow their study. These studies are framed...

Artificial organoids generated from cancer cells

Organoids mimic therapies responses We have published several articles about Potential applications of organoids that mimic different organs. We concluded that this creation of organic structures (organoids) similar to others in our body may have objective biomedical...

Pulmonary organoids produced from human iPS cells in three dimensions (3D)

Lung organoids have been produced from human pluripotent stem (iPS) cells that contain various components of lung tissue, and even airways and alveolar structures (see HERE). Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D)...

Cerebral organoids produced from embryonic stem cells

A group of researchers in La Jolla, California, have produced three-dimensional  cerebral organoids (“mini-brains”) from human embryonic stem cells, later comparing the functionality of the tissue produced with samples of brain tissue from human foetuses with the same...

Organoids. Mini-kidneys produced with iPS cells

Regenerating or producing a kidney is very complex — if not impossible right now — since more than 20 different types of cells need to be produced. However, the production of organoids mini kidneys (mini-organs) could be a preliminary step towards generating functioning kidneys....

Potential application of organoids that mimic different organs

In 2011, almost incidentally, Madeline Lancaster of the Institute of Molecular Biotechnology in Vienna managed to produce primitive retina cells and different nerve cells from embryonic stem cells. However, Lancaster and her colleagues were not the first to produce a brain...

Stem cells and the production of organoids at the forefront of biomedical science

There are topics in which biomedical interest merges with ethical interest. One of these is undoubtedly the subject of stem cells wich appears to be the biomedical science forefront. Few issues in the biomedical sciences arouse as much interest as these, and for this reason, the...

JME publication. Importance of philosophy in the context of medical ethics. “The most profound questions that health professionals face are not scientific or technical, but ethical”

Last July, an article was published in the Journal of Medical Ethics (JME) by outgoing editors Julian Savulescu, Thomas Douglas and Dominic Wilkinson, in which they reflect on the importance of philosophy in the context of medical ethics, as their term as editors of the journal...

Neuroscience. New experiments with brain rekindle the bioethical debate

Neuroscience research, with the ultimate goal of deepening our knowledge of the human brain, about which we still know so little, is advancing rapidly (see HERE). Thus, major projects such as the “BRAIN Initiative” in the United States and the Human Brain Project (HBP) in Europe...

Cardiac muscle cells, that drive the beating of the heart, developed from iPS cells

Cardiomyocytes produced with success One of the possibilities for the clinical-experimental use of iPS cells is to develop human-like tissues -organoids- for use in basic research or in preclinical therapeutic studies. Now, using iPS cells obtained from primates, a team from...
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