First major step in the treatment of blood diseases from adult cells

Researchers at Weill Cornell Medicine  have developed an innovative method for obtaining blood cells (adult cells) from the endothelial cells of blood vessels (see HERE) to imporove blood diseases treatment. A peculiar characteristic of this technique is that abundant blood cells...

Adult cells reprogramming technique (iPS) has been improved

One problem in reprogramming adult cells, using the technique proposed by Yamanaka in 2006, is that the percentage of cells reprogrammed is low, and not all are reprogrammed at the same time. Now, it appears that this problem has been resolved, after Israeli scientists developed...
Posted On 04 Jul 2014
, By

Adult stem cells could effectively substitute embryonic cells in regenerative medicine

Many technics showed that adult stem cells could effectively substitute embryonic cells in cellular therapy. One medical and ethical problem to resolve is to find adequate substitute for the use of embryonic stem cells in regenerative and reparatory medicine. The best possibility...

A HIV carrier cured using adult stem cells

The news that a patient carrying the HIV virus was cured by way of a transplant using hematopoietic stem cell (blood cells) has given rise to a renewed hope in the treatment of HIV patients. Stem cells coming from the patient can be used (autotransplantation) or from another...
Posted On 31 Mar 2014
, By

US authorizes the use of CRISPR directly in the patient’s body, until now the trials was made in cells extracted of the patient

Hopes and and concerns The first clinical trial involving the use of the gene editing tool CRISPR directly in the patient (see more ) has been approved in the United States. The trial aim to treat a congenital blindeness will include around 15 patients, adults and children, in...

Human-mouse hybrids created with sperm produced from human testicular stem cells

According to a recent article (see HERE), a team of researchers has managed to produce human functional spermatids (as sperm precursor cells are known) from human spermatogonial stem cells (SSC), testicular sperm cell precursors.  The SSCs were isolated and identified...

First treatment using gene therapy, to children and adults, approved in the United States

The first treatment using gene therapy is for a serious genetic disease -Inherited Retinal Dystrophy (RD) -that causes vision loss and even blindness. The drug used is called Voretigene neparvovec-rzyl, commercial name LUXTURNA, and is indicated for patients who present with...

For now, iPS cells have revolutionized the laboratory bench more than bedside

In a recent article, Amélie Rezza discussed the current use of iPS cells, understanding as such adult cells reprogrammed following a technique discovered by Yamanaka. See HERE our site for furthermore information. After the development of these cells, it was thought that they...

Pluripotent stem cells used for regenrative medicine risks. They can develop mutations that favor the production of cancer cells

It should be crucial to check pluripotent cell lines (embryonic and iPS cells) before clinical testing before their use in regenerative medicine The production of pluripotent stem cells, from which virtually all types of cells can be obtained, may be of great use for the...

The future of iPS – induced pluripotent stem cells. New finding increases tremendously their potential for clinical use

Cells now can be obtained from anonymous donors, however, and stored in a cell bank, the costs would be reduced significantly, and their potential for clinical use would increase tremendously A recent article published in Nature discussed some specific aspects regarding the...